Intel Flow Director (ntuple) filters require the NIC and driver to support the feature. To check if it is supported use ethtool -k or ethtool --show-features:
# ethtool -k enp5s0f0 | grep ntuple
ntuple-filters: on
The above output is from an Intel X710 NIC (i40e driver). If there is no output the hardware most likely does not support ntuple filters.